So in studying and reading about the Endocrine System, I feel like I have a good grasp on the concepts, so I went looking for ways that the Endocrine System screws up, cause that is what I really like...pathology. These are some of the Endocrine System disorders: diabetes mellitus (a diminished ability to create new RBC during chronic renal failure), cancer, thyroid disease, and obesity.
Endocrinopathies are classified as primary, secondary, or tertiary. Primary endocrine disease inhibits the action of downstream glands. Tertiary endocrine disease is associated with dysfunction of the hypothalamus and its releasing hormones. I couldn't find what the secondary classification was...anyone have a guess?
Cancer can occur in endocrine glands, such as the thyroid, and hormones have been implicated in signalling distant tissues to proliferate, for example the Estrogen receptor has been shown to be involved in certain breast cancers. Endocrine, Paracrine, and Autocrine signalling have all been implicated in proliferation, one of the required steps of oncogenesis. It just amazes me that with one small change in one small cell anywhere in the body, can create such chaos, such as cancer. It is especially frightening within the Endocrine System, especially because the system itself is designed to travel throughout the body, reaching every cell, so if cancer is present, it is virtually all over your body all at once...
Well, that's all for now...moving on to the blood. See you all on Tuesday! Aimee
3 comments:
Hi Aimee,
I couldn't agree with you more. It seemed like forever since we were in A&P last. At least we started with one of my favorite subjects. The Endocrine system is an amazing system, yet to me, kind of scary. It is responsible for such scary things. Diabetes is so over powering in this world. I am going to research and try to find the answer to your question. In the meantime we really need to set a time aside to start putting our game together. See you Tuesday!
Michelle
I too have an interest here. My wife was diagnosed with type II diabetes about 11 years ago. She initially had to take insulin shots but has since switched over to oral meds. Great comments. See you in class next week.
Bill
hey!! thanks for responding to my blog. oh nice page by the way. looks familiar ;-)
yeah, cancer is scary. i know of a woman who had it in her brain for years before they discovered it, and last i knew she was having a surgery that may leave her a totally different person and may not get rid of it all cause it's allll over the place. ugh. that is awful. makes me think we should all get tested for brain cancer once a year.
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